Bridging Biology to Quantitation: A Roadmap to Meaningful Potency Measurement For AAV-Based Gene Therapy
12:15 pm - Thursday 3rd December 2026
- Critical considerations for AAV gene therapies include cell line selection, culture and transduction conditions, plate configuration, sample concentration & dilution strategies, assay controls, and data analysis approaches.
- In this presentation, we will describe the development of a robust potency assay for a novel AAV9-like viral vector.
- The presentation will highlight assay development, data analysis strategies, qualification outcomes, and the demonstration of stability-indicating properties, providing a practical roadmap for developing a potency assay suitable for drug release and stability studies.
